Open grants › Grants for small businesses
Grants for small businesses
75 federal grants are open for applications right now and open to small businesses. The next deadline is October 14, 2026. On this page, most come from National Institutes of Health, U.S. National Science Foundation, Defense Health Agency Contracting Activity - DHACA.
Grants.gov lists small businesses, or any applicant, as eligible for each of these. Most federal funding for businesses is for research and development rather than general operating costs.
Want only the ones that fit your organization and state? Answer three questions and SeeGrant narrows this list for you. No account needed.
Match grants to my organization- DoW Melanoma Research Program Team Science Award
- DoW Melanoma Research Program Focused Program Award – Rare Melanomas
- The DOE Quantum Genesis Q Competition
- BJA FY 2026 Tribal Justice Training and Technical Assistance Program
- DoW Arthritis Translational Research Award
- FY2026 Implementation of the Quagga and Zebra Mussel Action Plan (QZAP) in the Western United States
- NASA Innovative Advanced Concepts (NIAC) Phase I
- OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance
- OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) Technological Investigative Capacity
- HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)
- BJA FY 2026 National Center for Veterans Justice
- OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support
- BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA)
- Exploring and Enhancing Outdoor and Heritage Tourism in the Chesapeake Bay Watershed
- Data Coordinating Center for the Aging and Alzheimer's Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)
- Pilot Projects to Enhance the Human Virome Program (R03 Clinical Trials Not Allowed)
- DoW Vision, Translational Research Award
- OJJDP FY 2026 Internet Crimes Against Children On-Line Child Protection System (ICACCOPS)
- NIJ FY 2026 Evaluation of the Effectiveness of the Bureau of Justice Assistance (BJA) Byrne State Crisis Intervention Program (SCIP)
- NIJ FY 2026 Research and Evaluation on Human Trafficking
- NIJ FY 2026 Research and Evaluation on Justice System Responses to Illegal Immigration
- NIJ FY 2026 Crime and Justice Research
- DoW Breast Cancer, Breakthrough Award Levels 1 and 2
- DoW Breast Cancer, Clinical Research Extension Award
- Easement Restoration and Stewardship
- NIJ FY 2026 Research and Evaluation on School Safety
- Cellular Senescence Network (SenNet): SenNet Technology Projects (SenTecs) (UG3/UH3 Clinical Trial Not Allowed)
- Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)
- NIJ FY 2026 Research on Gender Dysphoria and Violent Crime
- OVC FY 2026 Specialized Human Trafficking Assistance: Task Forces and Legal Services
- John H. Prescott Marine Mammal Rescue Assistance Grant
- Accelerating Scale-up and Pre-piloting of Emerging Chemical Technologies (ASPECT)
- Silicon Carbide Cladding Lead Test Rod Development-Phase 1
- MPPEP Phase 3 Invasive Wild-Caught Catfish
- Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)
- Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)
- Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)
- IGVF Data and Coordinating Center (U24 Clinical trials Not Allowed)
- SEFSC Bluefin Tuna Research Program
- Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)
- Human Networks and Data Science (HNDS)
- National Bycatch Reduction Engineering Program (BREP) - FY2026/27
- HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)
- HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
- Agriculture Innovation Center Grant Program
- Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances (U01 Clinical Trial Not Allowed)
- Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)
- Deployed Warfighter Protection FY27
- F26AS00105 National Fish Passage Program
- Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)
- Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)
- FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program
- Mechanistic Evaluation of Therapeutic Targets derived from Treatable Traits to Improve CNS Outcomes in People with HIV (R21/R33 Clinical Trial Not Allowed)
- Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)
- Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76 Clinical Trial Not Allowed)
- INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
- Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
- BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)
- Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)
- Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional)
- Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) (R03 Clinical Trial Optional)
- Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)
- BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed)
- NIAMS P30 Centers Program (P30 - Clinical Trial Not Allowed)
- NINDS Efficacy and Exploratory Clinical Trials (UG3/UH3 - Clinical Trial Required)
- NIH Brain Development Cohorts (NBDC) and Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01 Clinical Trial Not Allowed)
- Limited Competition: Institutional Development Award (IDeA) for Clinical & Translational Research (CTR) (P30 - CT Optional)
- Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)
- NEI Translational Research Program for Therapeutics (R61/R33 Clinical Trial Not Allowed)
- Geosciences Core Research: Atmospheric, Geospace, Earth and Ocean Sciences (GEO Core)
- Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)
- Engineering (ENG): Chemical, Bioengineering, Energy, and Transport Systems (CBET)
- Engineering (ENG): Electrical, Communications, and Computing Systems (ECCS)
- MPS Physics Research Programs (MPS Physics)
- MPS Astronomical Sciences Research Programs (MPS Astro)
Related grant lists
- Health grants for small businesses
- Research grants for small businesses
- Technology grants for small businesses
Updated daily from Grants.gov. SeeGrant is not affiliated with any federal agency. Confirm eligibility and deadlines on the official announcement before applying.