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Research grants for small businesses
29 federal grants are open for applications right now with research in the title and open to small businesses. The next deadline is October 14, 2026. On this page, most come from National Institutes of Health, Defense Health Agency Contracting Activity - DHACA, National Institute of Justice.
Grants.gov lists small businesses, or any applicant, as eligible for each of these. Most federal funding for businesses is for research and development rather than general operating costs.
Want only the ones that fit your organization and state? Answer three questions and SeeGrant narrows this list for you. No account needed.
Match grants to my organization- DoW Melanoma Research Program Team Science Award
- DoW Melanoma Research Program Focused Program Award – Rare Melanomas
- DoW Arthritis Translational Research Award
- DoW Vision, Translational Research Award
- NIJ FY 2026 Research and Evaluation on Human Trafficking
- NIJ FY 2026 Research and Evaluation on Justice System Responses to Illegal Immigration
- NIJ FY 2026 Crime and Justice Research
- DoW Breast Cancer, Clinical Research Extension Award
- NIJ FY 2026 Research and Evaluation on School Safety
- NIJ FY 2026 Research on Gender Dysphoria and Violent Crime
- SEFSC Bluefin Tuna Research Program
- Human Networks and Data Science (HNDS)
- HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
- Agriculture Innovation Center Grant Program
- FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program
- Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)
- INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
- Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
- BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)
- Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional)
- Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) (R03 Clinical Trial Optional)
- BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed)
- Limited Competition: Institutional Development Award (IDeA) for Clinical & Translational Research (CTR) (P30 - CT Optional)
- Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)
- NEI Translational Research Program for Therapeutics (R61/R33 Clinical Trial Not Allowed)
- Geosciences Core Research: Atmospheric, Geospace, Earth and Ocean Sciences (GEO Core)
- Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)
- MPS Physics Research Programs (MPS Physics)
- MPS Astronomical Sciences Research Programs (MPS Astro)
Related grant lists
- Health grants for small businesses
- Research grants for nonprofits
- Research grants for individuals
- Technology grants for small businesses
Updated daily from Grants.gov. Topics are matched on words in each grant's title, so a relevant grant with an unusual title may be missing. SeeGrant is not affiliated with any federal agency. Confirm eligibility and deadlines on the official announcement before applying.